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Gene Silencing
Gene Silencing
ROS1, a Repressor of Transcriptional Gene Silencing in Arabidopsis, Encodes a DNA Glycosylase/Lyase
DNA repair / Gene Silencing / Biological Sciences / Mutation / Cell / DNA methylation / Arabidopsis / Molecular cloning / Amino Acid Sequence / Base Sequence / Transcriptional gene silencing (TGS) / Molecular Sequence Data / DNA methylation / Arabidopsis / Molecular cloning / Amino Acid Sequence / Base Sequence / Transcriptional gene silencing (TGS) / Molecular Sequence Data
Genetic unmasking of epigenetically silenced tumor suppressor genes in colon cancer cells deficient in DNA methyltransferases
Genetics / Epigenetics / Transcription Factors / Gene Silencing / Colorectal cancer / Biological Sciences / DNA / Cell line / Humans / Female / Calcium channels / Nucleic acid hybridization / Male / Human Molecular Genetics / DNA methylation / CpG islands / Calcium Channel / Tumor Suppressor Gene / Colon cancer / Gene Targeting / Epigenetica / CpG island / Biological Sciences / DNA / Cell line / Humans / Female / Calcium channels / Nucleic acid hybridization / Male / Human Molecular Genetics / DNA methylation / CpG islands / Calcium Channel / Tumor Suppressor Gene / Colon cancer / Gene Targeting / Epigenetica / CpG island
MicroRNA genes are transcribed by RNA polymerase II
MicroRNA / RNA polymerase / Gene Silencing / Biological Sciences / RNA interference / Cell line / Humans / Chromatin / microRNAs / HeLa cells / Chromatin Immunoprecipitation / Base Sequence / Gene Expression Regulation / Molecular Sequence Data / Cell line / Humans / Chromatin / microRNAs / HeLa cells / Chromatin Immunoprecipitation / Base Sequence / Gene Expression Regulation / Molecular Sequence Data
Local RNA Target Structure Influences siRNA Efficacy: A Systematic Global Analysis
Thermodynamics / Molecular Biology / Computational Biology / Gene Silencing / Global Analysis / Genetic Engineering / Molecular / RNA interference / Cercopithecus aethiops / Cell line / Humans / RNAi / Animals / Drug Design / Free Energy / Rats / dsRNA / Substrate Specificity / Fluorescent Protein / Transfection / siRNA / RNA Structure / Base Sequence / TRP / UTR / GFP / Nucleic Acid Conformation / Biochemistry and cell biology / Enterovirus / Genetic Engineering / Molecular / RNA interference / Cercopithecus aethiops / Cell line / Humans / RNAi / Animals / Drug Design / Free Energy / Rats / dsRNA / Substrate Specificity / Fluorescent Protein / Transfection / siRNA / RNA Structure / Base Sequence / TRP / UTR / GFP / Nucleic Acid Conformation / Biochemistry and cell biology / Enterovirus
Local RNA Target Structure Influences siRNA Efficacy: A Systematic Global Analysis
Thermodynamics / Molecular Biology / Computational Biology / Gene Silencing / Global Analysis / Genetic Engineering / Molecular / RNA interference / Cercopithecus aethiops / Cell line / Humans / RNAi / Animals / Drug Design / Free Energy / Rats / dsRNA / Substrate Specificity / Fluorescent Protein / Transfection / siRNA / RNA Structure / Base Sequence / TRP / UTR / GFP / Nucleic Acid Conformation / Biochemistry and cell biology / Enterovirus / Genetic Engineering / Molecular / RNA interference / Cercopithecus aethiops / Cell line / Humans / RNAi / Animals / Drug Design / Free Energy / Rats / dsRNA / Substrate Specificity / Fluorescent Protein / Transfection / siRNA / RNA Structure / Base Sequence / TRP / UTR / GFP / Nucleic Acid Conformation / Biochemistry and cell biology / Enterovirus
In vivo trans-specific gene silencing in fungal cells by in planta expression of a double-stranded RNA
Biology / Tobacco / Scanning Electron Microscopy / RNA silencing / Gene expression / Gene Silencing / Biological Sciences / RNA interference / Fusarium / Polymerase Chain Reaction / Filamentous fungi / Vascular Plants / double-stranded RNA / Plant Leaves / Gene Silencing / Biological Sciences / RNA interference / Fusarium / Polymerase Chain Reaction / Filamentous fungi / Vascular Plants / double-stranded RNA / Plant Leaves
miR133a regulates cardiomyocyte hypertrophy in diabetes
Endocrinology / Micro Rna / Regulation / Gene Silencing / RNA interference / miRNA / Hemodynamics / Mice / Animals / Male / Clinical Sciences / Reviews / microRNAs / Rats / Heart Ventricles / Cell Survival / Gene Expression Regulation / miRNA / Hemodynamics / Mice / Animals / Male / Clinical Sciences / Reviews / microRNAs / Rats / Heart Ventricles / Cell Survival / Gene Expression Regulation
Long-lasting in vivo gene silencing by electrotransfer of shRNA expressing plasmid
Genetics / Skeletal muscle biology / Gene Silencing / Humans / Muscle / Mice / Electroporation / Female / Animals / shRNA / Gene / Plasmids / Green Fluorescent Protein / In Vivo / Gen / Transfection / Silencing / Plasmid / GFP / Mice / Electroporation / Female / Animals / shRNA / Gene / Plasmids / Green Fluorescent Protein / In Vivo / Gen / Transfection / Silencing / Plasmid / GFP
Arachidonic acid induces brain endothelial cell apoptosis via p38-MAPK and intracellular calcium signaling
Inflammation / Calcium / Mitochondria / Apoptosis / Gene Silencing / RNA interference / Microvascular Physiology / Brain / Humans / Endothelial Cells / Lipoxygenases / Calcium Signaling / Mitogen Activated Protein Kinase / Clinical Sciences / Caspase / Cell Proliferation / Arachidonic Acid / RNA interference / Microvascular Physiology / Brain / Humans / Endothelial Cells / Lipoxygenases / Calcium Signaling / Mitogen Activated Protein Kinase / Clinical Sciences / Caspase / Cell Proliferation / Arachidonic Acid
Arachidonic acid induces brain endothelial cell apoptosis via p38-MAPK and intracellular calcium signaling
Inflammation / Calcium / Mitochondria / Apoptosis / Gene Silencing / RNA interference / Microvascular Physiology / Brain / Humans / Endothelial Cells / Lipoxygenases / Calcium Signaling / Mitogen Activated Protein Kinase / Clinical Sciences / Caspase / Cell Proliferation / Arachidonic Acid / RNA interference / Microvascular Physiology / Brain / Humans / Endothelial Cells / Lipoxygenases / Calcium Signaling / Mitogen Activated Protein Kinase / Clinical Sciences / Caspase / Cell Proliferation / Arachidonic Acid
RNA Polymerase IV Directs Silencing of Endogenous DNA
Science / RNA polymerase / Multidisciplinary / Gene Silencing / RNA interference / Mutation / DNA methylation / Oryza Sativa / Arabidopsis / Chromatin / Amino Acid Sequence / Base Sequence / Molecular Sequence Data / Mutation / DNA methylation / Oryza Sativa / Arabidopsis / Chromatin / Amino Acid Sequence / Base Sequence / Molecular Sequence Data
Uptake and intracellular traffic of siRNA dendriplexes in glioblastoma cells and macrophages
Nanomedicine / Macrophages / Nanotechnology / Dendrimers / Gene Silencing / Humans / Mice / Endocytosis / Glioblastoma / Animals / Analysis of Variance / Biological markers / Cell Survival / Endosomes / Intracellular Space / Clathrin / Humans / Mice / Endocytosis / Glioblastoma / Animals / Analysis of Variance / Biological markers / Cell Survival / Endosomes / Intracellular Space / Clathrin
A transcriptional switch underlies commitment to sexual development in malaria parasites
Biology / Malaria / Medicine / Multidisciplinary / Gene Silencing / Nature / Germ Cells / Female / Animals / Parasites / Male / Plasmodium falciparum / Sex Differentiation / Sexual Development / Protozoan Proteins / DNA binding proteins / Gene Expression Regulation / Nature / Germ Cells / Female / Animals / Parasites / Male / Plasmodium falciparum / Sex Differentiation / Sexual Development / Protozoan Proteins / DNA binding proteins / Gene Expression Regulation
Silencing α-Synuclein Gene Expression Enhances Tyrosine Hydroxylase Activity in MN9D Cells
Gene expression / Gene Silencing / Western blotting / Alpha Synuclein / Biological Sciences / RNA interference / Dopamine / Humans / Plasmids / Levodopa / Tyrosine Hydroxylase / Enzyme / High Pressure Liquid Chromatography / Fluorescent Antibody Technique / Transfection / Cell Survival / Neurochemical / Down-Regulation / RNA interference / Dopamine / Humans / Plasmids / Levodopa / Tyrosine Hydroxylase / Enzyme / High Pressure Liquid Chromatography / Fluorescent Antibody Technique / Transfection / Cell Survival / Neurochemical / Down-Regulation
Knockdown of Hsc70-5/mortalin Induces Loss of Synaptic Mitochondria in a Drosophila Parkinson’s Disease Model
Engineering / Physics / Chemistry / Biology / Mitochondria / Autophagy / Medicine / Multidisciplinary / Gene Silencing / Drosophila / Humans / Female / Animals / Neurons / Phenotype / PLoS one / SYNAPSES / Cell Survival / Dopaminergic Neurons / Parkinson Disease / Autophagy / Medicine / Multidisciplinary / Gene Silencing / Drosophila / Humans / Female / Animals / Neurons / Phenotype / PLoS one / SYNAPSES / Cell Survival / Dopaminergic Neurons / Parkinson Disease
Aiolos promotes anchorage independence by silencing p66Shc transcription in cancer cells
Cell Adhesion / Gene Silencing / Humans / Lung / Chromatin / Cancer Cell / Cell Proliferation / Cell communication / Neurosciences / Gene expression profiling / Lymphopoiesis / Cancer Cell / Cell Proliferation / Cell communication / Neurosciences / Gene expression profiling / Lymphopoiesis
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